Tuesday
Aug232016

Investigating the Interplay between Sister Chromatid Cohesion and Homolog Pairing in Drosophila Nuclei

Senaratne TN, Joyce EF, Nguyen SC, Wu CT
PLoS Genet. 2016 Aug 19; http://dx.doi.org/10.1371/journal.pgen.1006169
Monday
Aug012016

Spatial organization of chromatin domains and compartments in single chromosomes

Wang S, Su J-H, Beliveau BJ, Bintu1 B, Moffitt1 JR, Wu CT, Zhuang X.
Science 21 Jul 2016. doi: 10.1126/science.aaf8084
Thursday
Apr142016

Pairing and anti-pairing: a balancing act in the diploid genome

Joyce EFErceg JWu CT

Curr Opin Genet Dev. 2016 Apr 8;37:119-128. doi: 10.1016/j.gde.2016.03.002 (LINK)

Monday
Feb012016

Genes with monoallelic expression contribute disproportionately to genetic diversity in humans.

Savova V, Chun S, Sohail M, McCole RB, Witwicki R, Gai L, Lenz TL, Wu CT, Sunyaev SR, Gimelbrant AA.

Nat Genet. 2016 Jan 25. doi: 10.1038/ng.3493. [Epub ahead of print].  PMID: 26808112

 

Friday
Jan152016

Super-resolution imaging reveals distinct chromatin folding for different epigenetic states

Boettiger AN, Bintu B, Moffitt JR, Wang S, Beliveau BJ, Fudenberg G, Imakaev M, Mirny LA, Wu CT, Xiaowei Zhuang X.

Nature 2016 Jan 13. doi: 10.1038/nature16496. Epub 2016 Jan 13 (Pubmed)

Monday
Nov162015

Scalable amplification of strand subsets from chip-synthesized oligonucleotide libraries.

Schmidt TL, Beliveau BJ, Uca YO, Theilmann M, Da Cruz F, Wu CT, Shih WM

Nat Commun. 2015 Nov 16;6:8634. doi: 10.1038/ncomms9634. (link)

Monday
Jun012015

Allelic Imbalance Is a Prevalent and Tissue-Specific Feature of the Mouse Transcriptome.

Pinter SF, Colognori D, Beliveau BJ, Sadreyev RI, Payer B, Yildirim E, Wu CT, Lee JT.

Genetics. 2015 Jun;200(2):537-49. doi: 10.1534/genetics.115.176263. Epub 2015 Apr 9. (pubmed)

Monday
Jun012015

Combined in vitro transcription and reverse transcription to amplify and label complex synthetic oligonucleotide probe libraries.

Murgha Y, Beliveau B, Semrau K, Schwartz D, Wu CT, Gulari E, Rouillard JM.

Biotechniques2015 Jun 1;58(6):301-7. doi: 10.2144/000114298. eCollection 2015 Jun. PMID:26054766

Friday
May082015

Single-molecule super-resolution imaging of chromosomes and in situ haplotype visualization using Oligopaint FISH probes. 

BJ Beliveau, AN Boettiger, MS Avendaño, R Jungmann, RB McCole, EF Joyce, C Kim-Kiselak, F Bantignies, CYFonseka, J Erceg, MA Hannan, HG Hoang, D Colognori, JT Lee, WM Shih, P Yin, X Zhuang, C-t Wu

Nature Communications 2015. May 12; 6:7147. doi: 10.1038/ncomms8147 (pubmed).

Thursday
Oct302014

Abnormal dosage of ultraconserved elements is highly disfavored in healthy cells but not cancer cells.

McCole RB, Fonseka CY, Koren A, Wu CT.

PLoS Genet. 2014 Oct 23;10(10):e1004646. doi: 10.1371/journal.pgen.1004646

Paper

Thursday
Jan232014

Visualizing Genomes with Oligopaint FISH Probes.

Beliveau BJ, Apostolopoulos N, Wu CT.

Current Protocols in Molecular Biology  2014. 105:14.23.1–14.23.20.

Link

Friday
Jan102014

Germline Progenitors Escape the Widespread Phenomenon of Homolog Pairing during Drosophila Development.

Joyce EF, Apostolopoulos N, Beliveau BJ, Wu CT.

PLoS Genet. 2013 Dec;9(12):e1004013. doi: 10.1371/journal.pgen.1004013. Epub 2013 Dec 19.

Paper

Wednesday
Jan022013

Versatile deign and synthesis platform for visualizing genomes with Oligopaint FISH probes.

Beliveau BJ, Joyce EF, Apostolopoulos N, Yilmaz F, Fonseka CY, McCole RB, Li JB, Senaratne TN, Williams BR, Rouillard JM, Wu CT.

Proc Natl Acad Sci USA. 2012. 109(52):21301-6

Pubmed

Wednesday
Sep052012

Restoration of Topoisomerase 2 function by complementation of defective monomers in Drosophila.

Hohl AM, Thompson M, Soshnev AA, Wu J, Morris J, Hsieh T-S, Wu C-t, Geyer PK.

Genetics. 2012 Aug 24 (in press)
Pubmed

Tuesday
Apr172012

Identification of genes that promote or antagonize somatic homolog pairing using a high-throughput FISH-based screen.

Joyce EF, Williams BR, Xie T, Wu C-t.

PLoS Genet 2012. 8(5): e1002667. doi:10.1371/journal.pgen.1002667
Article

Wednesday
Nov102010

Effects of chromosomal rearrangements on transvection at the yellow gene of Drosophila melanogaster.

Ou SA, Chang E, Lee S, So K, Wu CT, Morris JR.

Genetics. 2009 Oct;183(2):483-96. Epub 2009 Aug 10.
Pubmed

Wednesday
Nov102010

The twin spot generator for differential Drosophila lineage analysis.

Griffin R, Sustar A, Bonvin M, Binari R, del Valle Rodriguez A, Hohl AM, Bateman JR, Villalta C, Heffern E, Grunwald D, Bakal C, Desplan C, Schubiger G, Wu CT, Perrimon N.

Nat Methods. 2009 Aug;6(8):600-2. Epub 2009 Jul 26.
Pubmed
Wednesday
Nov102010

Molecular genetic analysis of Suppressor 2 of zeste identifies key functional domains

Emmons RB, Genetti H, Filandrinos S, Lokere J, Wu CT. 

Genetics. 2009 Aug;182(4):999-1013. Epub 2009 Jun 15.
Pubmed
Wednesday
Nov102010

Ultraconserved elements: analyses of dosage sensitivity, motifs and boundaries

Chiang CW, Derti A, Schwartz D, Chou MF, Hirschhorn JN, Wu CT.

Genetics. 2008 Dec;180(4):2277-93. Epub 2008 Oct 28.
Pubmed
Wednesday
Nov102010

A simple polymerase chain reaction-based method for the construction of recombinase-mediated cassette exchange donor vectors.

Bateman JR, Wu CT.

Genetics. 2008 Nov;180(3):1763-6. Epub 2008 Sep 14.
Pubmed